Common painkiller fights skin cancer

Subject:Common painkiller fights skin cancer
Date:06 Jan 2010 18:24:15 GMT
Common painkiller fights skin cancer
Wed, 06 Jan 2010 14:32:28 GMT

The commonly used painkiller known as celecoxib (Celebrex)
has shown promising results in protecting individuals
against certain types of skin cancer.

Previous studies had reported the efficacy of celecoxib in
treating squamous cell carcinoma, a common type of skin
cancer, on mice samples. The COX inhibitor is believed to
fight the disease through inhibiting the growth of new
vessels that are needed to nourish the tumor.

According to a study published in Cancer Prevention
Research, individuals with Gorlin syndrome, a condition
associated with genetic predisposition to a skin cancer
called basal cell carcinoma, are 50 percent less likely to
develop the condition when they are taking celecoxib.

The overall burden of the disease was also reported to be
lower among those on the non-steroidal anti-inflammatory
drug (NSAID). Celecoxib, however, was only effective in
those with mild forms of the disease, for instance, those
who had more than 15 skin lesions upon entering the study.

"Those with a lot of lesions may have other genetic
mutations that make their cancer more robust," said study
coauthor Jean Tang.

Many health officials, however, have cautioned over the
routine use of the disease, (sic - "Drug" instead)
stressing that the drug is associated with potential
cardiovascular risks in certain individuals.

PKH/HGH
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http://www.presstv.ir/detail.aspx?id=115499§ionid=3510210
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